Observe in background?

Hello, is it possible to start an observer in a specific region which continues in the background while the script continues, like sikulix?
If so, would someone please give me an example of it's usage?

With sikuli, it would be something like:
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def helpH(event):
    helpR.stopObserver()
    helpR.click(Pattern("helpImage.png")
    helpR.ObserveEvent.repeat()

def help():
    helpR.onAppear(Pattern("helpImage.png").similar(0.80), helpH)
    helpR.observe(background = True)
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The last line could also be "helpR.observeInBackground(FOREVER)".